Listar por autor "Zuckermann, Andreas"

Mostrando ítems 1-7 de 7

    • An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms 

      Parkes, Michael D.; Aliabadi, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Deng, Mario; Depasquale, Eugene C.; Goekler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Loupy, Alexandre; Macdonald, Peter; Potena, Luciano; Zuckermann, Andreas; Halloran, Philip F. (Elsevier, 2019-02-06)
      [Abstract] BACKGROUND. We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate ...

    • Analysis of donor-derived cell-free DNA with 3 year outcomes in heart transplant recipients 

      Crespo-Leiro, María Generosa; Hiller, David; Woodward, Robert N.; Grskovic, Marica; Marchis, C.; Song, Mindy; Collins, John P.; Zuckermann, Andreas (Elsevier, 2017)

    • Assessing the relationship between molecular rejection and parenchymal injury in heart transplant biopsies 

      Madill-Thomsen, Katelynn S.; Reeve, Jeff; Aliabadi-Zuckermann, Arezu; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene D.; Deng, Mario; Goeckler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; MacDonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Halloran, Philip F. (Wolters Kluwer, 2022-11)
      [Abstract] Background: The INTERHEART study (ClinicalTrials.gov #NCT02670408) used genome-wide microarrays to detect rejection in endomyocardial biopsies; however, many heart transplants with no rejection have late dysfunction ...

    • Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II 

      Crespo-Leiro, María Generosa; Stypmann, Jörg; Schulz, Uwe; Zuckermann, Andreas; Mohascsi, Paul; Bara, Christian; Ross, Heather; Parameshwar, Jayan; Zakliczynski, Michal; Fiocchi, Roberto; Hoefer, Daniel; Colvin, Monica; Deng, Mario; Leprince, Pascal; Elashoff, Barbara; Yee, James P.; Vanhaecke, Johan (Oxford University Press en nombre de European Society of Cardiology, 2016-01-07)
      [Abstract] Aims. A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study, Cardiac Allograft Rejection Gene Expression ...

    • Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies 

      Crespo-Leiro, María Generosa; Costanzo, María Rosa; Gustafsson, Finn; Khush, Kiran K.; Macdonald, Peter S.; Potena, Luciano; Stehlik, Josef; Zuckermann, Andreas; Mehra, Mandeep R. (Oxford Academic, 2022-06-14)
      [Abstract] Heart transplantation is advocated in selected patients with advanced heart failure in the absence of contraindications. Principal challenges in heart transplantation centre around an insufficient and underutilized ...

    • Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2021-08-04)
      [Abstract] Background: The Molecular Microscope (MMDx) system classifies heart transplant endomyocardial biopsies as No-rejection (NR), Early-injury, T cell-mediated (TCMR), antibody-mediated (ABMR), mixed, and possible ...

    • Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients 

      Crespo-Leiro, María Generosa; Stypmann, Jörg; Schulz, Uwe; Zuckermann, Andreas; Mohacsi, Paul; Bara, Christoph; Ross, Heather; Parameshwar, Jayan; Zakliczynski, Michal; Fiocchi, Roberto; Hoefer, Daniel; Deng, Mario; Leprince, Pascal; Hiller, David; Eubank, Emir; Yee, James P.; Vanhaecke, Johan (BioMed Central, 2015-10-09)
      [Abstract] Background. A single non-invasive gene expression profiling (GEP) test (AlloMap®) is often used to discriminate if a heart transplant recipient is at a low risk of acute cellular rejection at time of testing. ...